Supplementary Table 5 is also available in Excel format here.
| Viral lineages | Sequence | Nucleotide substitution rate (subs.site-1.year-1, 95% HPD) | Migration rate (migrations.year-1, 95% HPD) | Velocitya (km.year-1, 95% HPD) | Diffusion coefficient (km2.year-1, 95% HPD) | Factors facilitating spread | Factors preventing spread | Reference |
|---|---|---|---|---|---|---|---|---|
| Global |
N G |
2.3e-4 (1.1e-4 - 3.6e-4) 3.9e-4 (1.2e-4 - 6.5e-4) |
Bourhy et al., 2008 | |||||
| Africa 2 |
N G |
3.82e-4 (2.62e-4 - 5.02e-4) 3.25e-4 (2.22e-4 - 4.32e-4) |
Talbi et al., 2009 | |||||
| Africa 1 | N, P, intergenic G-L |
Algeria vGreat circle distances = 26 (18 - 34) vRoad distances = 33 (23 - 43) Morocco vGreat circle distances = 42 (26 - 58) vRoad distances = 51 (34 - 72) |
Roads | Talbi et al., 2010 | ||||
| Arctic, Cosmopolitan, Indian, SEA-1, SEA-2, SEA-3 | N | 4.316e-4 (3.11e-4 - 5.632e-4) | Meng et al., 2011 | |||||
| N | 1.519e-3c | Carnieli et al., 2011 | ||||||
| Asian | N |
clade I: 1.274e-3 (8.3705e-4 - 1.2515e-3) clade II: 9.629e-4 (3.519e-4 - 1.628e-3) |
Yu et al., 2012 | |||||
| Cosmopolitan, SEA-1, SEA-2, SEA-3 | N | 5.23e-4 (3.94e-4 - 6.68e-4) | Guo et al., 2013 | |||||
| N | 6.81e-4 (6.66e-4 - 6.96e-4) |
vOverall = 12.88b vDogs = 30.5b vCerdocyon thous = 9.0b |
Carnieli et al., 2013 | |||||
| Asian 2 | G | 5.81e-4 (4.47e-4 - 7.27e-4) | Tohma et al., 2014 | |||||
| Africa 1b | whole-genome | 1.44e-4 (5.78e-7 - 3.19e-4) | Brunker et al., 2015 | |||||
| Global |
N G |
2.18e-4 (1.68 - 2.71)d 3.20e-4 (2.60 - 3.80)d |
Troupin et al., 2016 | |||||
| Africa 1, Africa 2 | N, P, M, G, intergenic G-L | 5.9e-4 (4.4e-4 - 7.5e-4) | v = 0.9 (0.65 - 1.2) | Bourhy et al., 2016 | ||||
| Arctic, Cosmopolitan, Indian, SEA-1, SEA-2, SEA-3 | N | 1.88e-4 (1.37e-4 - 2.41e-4) | Zhang et al., 2017 | |||||
|
N G |
2.4e-4 (1.5e-4 - 3.2e-4) 3.4e-4 (2.7e-4 - 4.1e-4) |
Ma et al., 2017 | ||||||
| Africa 1 | N, P, intergenic G-L | vwavefront ~ 15 - 22b |
D = 2874 (1900 - 5420) Dweighted = 1305 (1086 - 1574) |
Grasslands Urban areas Human population density |
Inacessibility Elevation |
Dellicour et al., 2017 | ||
| Africa 1b | whole-genome | 2.67e-4b |
v = 4.46 (3.22 - 5.88) Coefficient of variation M = 3.10 |
Dog presence |
Elevation Rivers |
Brunker et al., 2018 | ||
| SEA-1, SEA-2, SEA-3 | N, G |
v = 57.5 (39.2 - 85.1) vweighted = 23.4 (2.4 - 32.6) |
D = 1733 (1082 - 2928) Dweighted = 1064 (116 - 1638) |
Forest coverage Spread towards forest coverage, croplands, accessible areas |
Tian et al., 2018 | |||
| Arctic-like 2, Central Asian 1, SEA-1, SEA-2, SEA-3, SEA-5 | N | 2.848e-4 (2.292e-4 - 3.449e-4) | 5.81e-3 (3.92e-3 - 7.77e-3) | Wang et al., 2019 | ||||
| whole-genome | 2.13e-4 (1.88e-4 - 2.35e-4) |
v = 55.5 (38.9 - 142.4) vweighted = 18.1 (16.3 - 20.8) |
D = 2676 (1935 - 5066) Dweighted = 1643 (1356 - 2325) |
Accessible areas Spread towards accessible areas associated with relatively high human population density |
Barren vegetation areas Spread towards grasslands |
Dellicour et al., 2019 | ||
| Note: | ||||||||
| Abbreviations: SEA-1, South-East Asia 1; SEA-2, South-East Asia 2; SEA-3, South-East Asia 3 | ||||||||
| a Depending on the study, estimates of RABV velocity were obtained with different methodologies. | ||||||||
| b 95% HPD intervals are not specified in the original papers | ||||||||
| c 95% HPD upper value | ||||||||
| d Median with the 95% HPD interval |